Serum Substitutes
Cayman Chemical SR 1555hydrochlorIde 5mg
A selective ligand of RORγ (IC50 = 1 μM); does not bind RORα, LXR, or FXR; acts as an inverse agonist of RORγ, inhibiting endogenous IL-17A gene expression and suppressing differentiation of TH17 cells; stimulates T regulatory development
ABclonal Technology SR-BI Rabbit pAb
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2.
Biolegend PerCP/Cyanine5.5 anti-mouse IFN-γ [W18272D]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg
PerCP/Cyanine5.5 anti-mouse IFN-γ [W18272D]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg
Biolegend FITC anti-mouse IFN-γ [W18272D]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg
FITC anti-mouse IFN-γ [W18272D]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: ICFC; Size: 100 μg
Cayman Chemical sR 128129E 25mg
An FGFR inhibitor (IC50 = 1.9 nM); reduces FGF2-induced endothelial cell proliferation and migration (IC50s = 31 and 15.2 nM, respectively); reduces proliferation of cells expressing FGFR1-4 at 100 nM; reduces disease severity and enhances physical performance in a mouse model of arthritis at 30 mg/kg per day; reduces tumor growth and metastasis in a Panc02 mouse orthotopic tumor model; reduces atherosclerotic lesion size in the aortic sinus of apoE-/- mice at 50 mg/kg per day; reduces intimal hyperplasia following jugular vein-to-artery bypass grafting surgery in rats
Biolegend Brilliant Violet 750™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 100 tests
Brilliant Violet 750™ anti-human IFN-γ [B27]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: ICFC; Size: 100 tests
Cayman Chemical SR 95531hydrobromIde 25mg
A derivative of GABA that acts as an antagonist of GABAA receptors (Ki = 74-150 nM); elicits seizures when administered intravenously in mice; effective against GABAA receptor isoforms from mice, rats, and humans
Cayman Chemical SR 57227AhydrochlorIde 25mg
A 5-HT3 receptor agonist; selectively binds 5-HT3 receptors (IC50 = 2.8 nM) over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT2, and 5-HT4 receptors (IC50s = >1,000 nM for all); induces contractions in isolated guinea pig ileum at 20 µM; intrastriatal administration induces contralateral turning behavior in mice at 1 UG/animal; reduces immobility time in the forced swim test in rats (ED50 = 7.6 mg/kg); reduces the number of escape failures in a rat model of learned helplessness and the duration of fighting in a mouse model of isolation-induced aggression